【产品概况】
产品名称:Human CD46 Antibody (FOR46, Research Use)
产品编号:NBR-0135
针对靶点:CD46
抗体药商品名:FOR46
抗体药描述:FOR46 is a novel antibody-drug conjugate (ADC) against CD46, for the treatment of metastatic castration-resistant prostate cancer and late-stage multiple myeloma.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD46
Synonyms: TLX; TRA2.10; MIC10; MCP
Target Description: CD46 (CD46 Molecule) is a Protein Coding gene. Diseases associated with CD46 include Hemolytic Uremic Syndrome, Atypical 2 and D-Minus Hemolytic Uremic Syndrome. Among its related pathways are Complement cascade and Immune response Lectin induced complement pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor activity and enzyme inhibitor activity. An important paralog of this gene is CR1.
Ensembl: ENSG00000117335
Uniprot: P15529