【产品概况】
产品名称:Human CD79b / Ig B Antibody (Polatuzumab, Research Use)
产品编号:NBR-0141
针对靶点:CD79b / Ig B
抗体药商品名:Polatuzumab
抗体药描述:Polatuzumab vedotin (INN; brand name Polivy, is an antibody-drug conjugate or ADC designed for the treatment of cancer. The US Food and Drug Administration approved polatuzumab vedotin in June 2019 for treatment of diffuse large B-cell lymphoma when used in combination with bendamustine and rituximab.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD79b / Ig B
Synonyms: B29; Ig-Beta; IGB
Target Description: CD79B (CD79b Molecule) is a Protein Coding gene. Diseases associated with CD79B include Agammaglobulinemia 6, Autosomal Recessive and Agammaglobulinemia, Non-Bruton Type. Among its related pathways are Antigen activates B Cell Receptor (BCR) leading to generation of second messengers and Disease. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity. An important paralog of this gene is CD79A.
Ensembl: ENSG00000007312
Uniprot: P40259