【产品概况】
产品名称:Human CLEC12A Antibody (Tepoditamab, Research Use)
产品编号:NBR-0151
针对靶点:CLEC12A
抗体药商品名:Tepoditamab
抗体药描述:Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds CLEC12A on myeloid cells and CD3ε on cytotoxic T cells. It is being developed by Merus as a novel therapy for acute myeloid leukemia (AML) .
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CLEC12A
Synonyms: DCAL-2; CLL-1; MICL; CD371
Target Description: CLEC12A (C-Type Lectin Domain Family 12 Member A) is a Protein Coding gene. Diseases associated with CLEC12A include Myeloid Leukemia and Mixed Phenotype Acute Leukemia, B/Myeloid. Among its related pathways are Innate Immune System and IL-1 Family Signaling Pathways. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC1A.
Ensembl: ENSG00000172322
Uniprot: Q5QGZ9