【产品概况】
产品名称:Human DLL4 Antibody (Demcizumab, Research Use)
产品编号:NBR-0162
针对靶点:DLL4
抗体药商品名:Demcizumab
抗体药描述:Demcizumab is a humanized monoclonal antibody which is used to treat patients with pancreatic cancer or non-small cell lung cancer. Demcizumab has completed phase 1 trials and is currently undergoing phase 2 trials.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: DLL4
Synonyms: Hdelta2; Delta; AOS6
Target Description: DLL4 (Delta Like Canonical Notch Ligand 4) is a Protein Coding gene. Diseases associated with DLL4 include Adams-Oliver Syndrome 6 and Adams-Oliver Syndrome. Among its related pathways are NOTCH2 Activation and Transmission of Signal to the Nucleus and Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants. Gene Ontology (GO) annotations related to this gene include calcium ion binding and Notch binding.
Ensembl: ENSG00000128917
Uniprot: Q9NR61