【产品概况】
产品名称:Human EPCAM Antibody (Citatuzumab, Research Use)
产品编号:NBR-0165
针对靶点:EPCAM
抗体药商品名:Citatuzumab
抗体药描述:Citatuzumab bogatox (VB6-845) is a monoclonal antibody Fab fragment fused with bouganin, a ribosome inactivating protein from the plant Bougainvillea spectabilis. It has undergone preclinical development for the treatment of ovarian cancer and other solid tumors.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: EPCAM
Synonyms: 17-1A; 323/A3; CD326; CO-17A; EGP-2; EGP34; EGP40; Ep-CAM; ESA; GA733-2; HEA125; KS1/4; KSA; Ly74; M4S1; MH99; MIC18; MK-1; MOC31; TACST-1; TACSTD1; TROP1
Target Description: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection.
Ensembl: ENSG00000119888
Uniprot: P16422