【产品概况】
产品名称:Human FAP Antibody (Sibrotuzumab, Research Use)
产品编号:NBR-0171
针对靶点:FAP
抗体药商品名:Sibrotuzumab
抗体药描述:Sibrotuzumab is a humanized monoclonal antibody intended for the treatment of cancer. It binds to FAP. In 2003 it failed a phase II clinical trial for metastatic colorectal cancer.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FAP
Synonyms: DPPIV
Target Description: FAP (Fibroblast Activation Protein Alpha) is a Protein Coding gene. Diseases associated with FAP include Breast Ductal Carcinoma and Melanoma. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and serine-type endopeptidase activity. An important paralog of this gene is DPP4.
Ensembl: ENSG00000078098
Uniprot: Q12884