【产品概况】
产品名称:Human Ferroportin Antibody (LY2928057, Research Use)
产品编号:NBR-0172
针对靶点:Ferroportin
抗体药商品名:LY2928057
抗体药描述:LY2928057 is a novel humanized IgG4 monoclonal antibody that binds to human ferroportin with a high affinity, blocks the binding of human hepcidin to ferroportin, and is a potent inhibitor of hepcidin activity in a recombinant ferroportin expressing HEK 293 cell-based assay.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Ferroportin
Synonyms: SLC40A1; FPN1; HFE4; IREG1; MTP1; SLC11A3
Target Description: SLC40A1 (Solute Carrier Family 40 Member 1) is a Protein Coding gene. Diseases associated with SLC40A1 include Hemochromatosis, Type 4 and Hemochromatosis, Type 1. Among its related pathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Disorders of transmembrane transporters. Gene Ontology (GO) annotations related to this gene include iron ion transmembrane transporter activity.
Ensembl: ENSG00000138449
Uniprot: Q9NP59