【产品概况】
产品名称:Human FGFR3 Antibody (LY3076226, Research Use)
产品编号:NBR-0176
针对靶点:FGFR3
抗体药商品名:LY3076226
抗体药描述:LY3076226 is an antibody-drug conjugate (ADC) comprising a fully human anti-FGFR3 antibody, IMC-D11, conjugated to a cytotoxic payload, the maytansine-derivative DM4, via a cleavable linker (sulfo-SPDB).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FGFR3
Synonyms: ACH; CD333; CEK2; JTK4
Target Description: FGFR3 (Fibroblast Growth Factor Receptor 3) is a Protein Coding gene. Diseases associated with FGFR3 include Achondroplasia and Hypochondroplasia. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR2.
Ensembl: ENSG00000068078
Uniprot: P22607