【产品概况】
产品名称:Human FLT3 Antibody (IMC-EB10, Research Use)
产品编号:NBR-0180
针对靶点:FLT3
抗体药商品名:IMC-EB10
抗体药描述:IMC-EB10 is an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell lines and primary leukemic samples.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FLT3
Synonyms: CD135; FLK2; STK1
Target Description: FLT3 (Fms Related Receptor Tyrosine Kinase 3) is a Protein Coding gene. Diseases associated with FLT3 include Leukemia, Acute Myeloid and Acute Myeloid Leukemia With Minimal Differentiation. Among its related pathways are crenolanib-resistant FLT3 mutants and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is KDR.
Ensembl: ENSG00000122025
Uniprot: P36888