【产品概况】
产品名称:Human GITR Antibody (Ragifilimab, Research Use)
产品编号:NBR-0186
针对靶点:GITR
抗体药商品名:Ragifilimab
抗体药描述:Ragifilimab is an anti-human glucocorticoid-induced tumor necrosis factor receptor (tumor necrosis factor superfamily, member 18; TNFRSF18; GITR; CD357) agonistic humanized monoclonal antibody, with potential immune checkpoint modulating activity. Ragifilimab binds to and activates GITRs found on multiple types of T cells.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: GITR
Synonyms:
Target Description: TNFRSF18 (TNF Receptor Superfamily Member 18) is a Protein Coding gene. Diseases associated with TNFRSF18 include Immunodysregulation, Polyendocrinopathy, And Enteropathy, X-Linked and Diverticulitis. Among its related pathways are Gene expression (Transcription) and Akt Signaling. Gene Ontology (GO) annotations related to this gene include tumor necrosis factor receptor activity. An important paralog of this gene is TNFRSF21.
Ensembl: ENSG00000010310
Uniprot: P48546