【产品概况】
产品名称:Human GPNMB Antibody (Glembatumumab, Research Use)
产品编号:NBR-0190
针对靶点:GPNMB
抗体药商品名:Glembatumumab
抗体药描述:Glembatumumab vedotin (also known as CDX-011 and CR011-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: GPNMB
Synonyms: HGFIN; NMB
Target Description: GPNMB (Glycoprotein Nmb) is a Protein Coding gene. Diseases associated with GPNMB include Amyloidosis, Primary Localized Cutaneous, 3 and Lichen Amyloidosis. Among its related pathways are Signaling by PTK6 and Signal Transduction. Gene Ontology (GO) annotations related to this gene include heparin binding and integrin binding. An important paralog of this gene is PMEL.
Ensembl: ENSG00000136235
Uniprot: Q14956