【产品概况】
产品名称:Human IGF-1R Antibody (Teprotumumab, Research Use)
产品编号:NBR-0209
针对靶点:IGF-1R
抗体药商品名:Teprotumumab
抗体药描述:Teprotumumab is a fully human monoclonal antibody that binds to the ligand binding extracellular alpha subunit of the IGF-1R (Figure 2). Formerly known as R1507, teprotumumab was first developed and studied with regards to its use for cancer therapy, but has fallen short of making significant differences in prognosis in multiple studies.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IGF-1R
Synonyms: CD221; IGFIR; IGFR; JTK13; MGC18216
Target Description: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control.
Ensembl: ENSG00000140443
Uniprot: P08069