【产品概况】
产品名称:Human IL-1RL2 Antibody (Imsidolimab, Research Use)
产品编号:NBR-0216
针对靶点:IL-1RL2
抗体药商品名:Imsidolimab
抗体药描述:Imsidolimab, previously known as ANB019, is an antibody that inhibits the function of the interleukin-36-receptor, or IL-36R, which we are developing as a potential first-in-class therapy for patients suffering from generalized pustular psoriasis (GPP) and moderate-to-severe hidradenitis suppurativa.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-1RL2
Synonyms: IL1R-rp2; IL1RRP2
Target Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity).
Ensembl: ENSG00000115598
Uniprot: Q9HB29