【产品概况】
产品名称:Human LOXL2 Antibody (Simtuzumab, Research Use)
产品编号:NBR-0239
针对靶点:LOXL2
抗体药商品名:Simtuzumab
抗体药描述:Simtuzumab (INN; formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: LOXL2
Synonyms: LOR; WS9-14
Target Description: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
Ensembl: ENSG00000134013
Uniprot: Q9Y4K0