【产品概况】
产品名称:Human NKG2A Antibody (Monalizumab, Research Use)
产品编号:NBR-0257
针对靶点:NKG2A
抗体药商品名:Monalizumab
抗体药描述:Monalizumab (IPH2201) is a potentially first-in-class immune checkpoint inhibitor targeting NKG2A receptors expressed on tumor infiltrating cytotoxic CD8+ T cells and NK cells.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: NKG2A
Synonyms: CD159a; NKG2; NKG2-A; NKG2-B
Target Description: Immune inhibitory receptor involved in self-nonself discrimination. In complex with KLRD1 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia molecules.
Ensembl: ENSG00000134545
Uniprot: P26715