【产品概况】
产品名称:Human PVRIG Antibody (GSK4381562, Research Use)
产品编号:NBR-0272
针对靶点:PVRIG
抗体药商品名:GSK4381562
抗体药描述:GSK4381562 is a differentiated anti-PVRIG antibody and represents a new therapeutic approach designed to enhance NK and T cell activation in the tumor microenvironment.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PVRI
Synonyms: GC7orf15; CD112R; MGC2463
Target Description: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Ensembl: ENSG00000213413
Uniprot: Q6DKI7