产品名称：Human PVRIG Antibody (COM701, Research Use)
产品编号：NBR-0273
针对靶点：PVRIG
抗体药商品名：COM701
抗体药描述：COM701 is a novel 1st in-class immune checkpoint inhibitor. Its mechanism of action can lead to enhanced activation of T and natural killer (NK) cells. The reasoning behind combining COM701 with the anti-TIGIT therapy, BMS-986207, and the immune checkpoint inhibitor, nivolumab, is to block the DNAM axis, making treatment more tolerable. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: PVRI
Synonyms: GC7orf15; CD112R; MGC2463
Target Description: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding. 
Ensembl: ENSG00000213413
Uniprot: Q6DKI7