【产品概况】
产品名称:Human RON Antibody (Narnatumab, Research Use)
产品编号:NBR-0276
针对靶点:RON
抗体药商品名:Narnatumab
抗体药描述:Narnatumab (IMC-RON8; LY3012219) is a neutralizing monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: RON
Synonyms: CD136; CDw136; PTK8; RON; SEA
Target Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules.
Ensembl: ENSG00000164078
Uniprot: Q04912