【产品概况】
产品名称:Human Sclerostin Antibody (Romosozumab, Research Use)
产品编号:NBR-0280
针对靶点:Sclerostin
抗体药商品名:Romosozumab
抗体药描述:Romosozumab is a monoclonal antibody used to treat osteoporosis in postmenopausal women at high risk of fracture, patients who are intolerant of other treatments, or patients who have failed other treatments.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Sclerostin
Synonyms: DAND6; VBC
Target Description: HMay be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling (By similarity). Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner.
Ensembl: ENSG00000167941
Uniprot: Q9BQB4