【产品概况】
产品名称:Human Tau Antibody (Gosuranemab, Research Use)
产品编号:NBR-0287
针对靶点:Tau
抗体药商品名:Gosuranemab
抗体药描述:Gosuranemab is an antibody directed against the N-terminus of tau. Target engagement was demonstrated with lowering of N-terminal tau in cerebrospinal fluid (CSF), consistent with prior studies.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Tau
Synonyms: DDPAC; FLJ31424; FTDP-17; MAPTL; MGC138549; MSTD; MTBT1; MTBT2; PPND; PPP1R103; tau
Target Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity . The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both.
Ensembl: ENSG00000186868
Uniprot: P10636