【产品概况】
产品名称:Human FLT1 / VEGFR1 Antibody (Icrucumab, Research Use)
产品编号:NBR-0301
针对靶点:FLT1 / VEGFR1
抗体药商品名:Icrucumab
抗体药描述:Icrucumab (IMC-18F1) is a human monoclonal antibody designed for the treatment of solid tumors. Icrucumab was developed by ImClone Systems Inc. It is undergoing Phase I trials.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FLT1 / VEGFR1
Synonyms: FLT; VEGFR1
Target Description: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. Acts as a positive regulator of postnatal retinal hyaloid vessel regression.
Ensembl: ENSG00000102755
Uniprot: P17948