【产品概况】
产品名称:Human Frizzled-10 Antibody (Tabituximab, Research Use)
产品编号:NBR-0303
针对靶点:Frizzled-10
抗体药商品名:Tabituximab
抗体药描述:Tabituximab is a radioimmunoconjugate composed of a humanized monoclonal antibody (MoAb) tabituximab barzuxetan against FZD10, with potential antineoplastic activity.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Frizzled-10
Synonyms: CD350
Target Description: Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.
Ensembl: ENSG00000111432
Uniprot: Q9ULW2