【产品概况】
产品名称:Human IL-22RA Antibody (ARGX-112, Research Use)
产品编号:NBR-0318
针对靶点:IL-22RA
抗体药商品名:ARGX-112
抗体药描述:ARGX-112 is a novel, fully human antibody neutralizing both IL20 and IL22 signaling through blockade of their common receptor, IL22R, with low picomolar potency. IL20 and IL22 are involved in proliferation and differentiation of keratinocytes (skin cells) and when over-expressed, are implicated in autoimmune diseases of the skin, including atopic dermatitis, psoriasis and pustular psoriasis.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-22RA
Synonyms: CRF2-9; IL22R
Target Description: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways.
Ensembl: ENSG00000142677
Uniprot: Q8N6P7