【产品概况】
产品名称:Human ILT7 Antibody (Daxdilimab, Research Use)
产品编号:NBR-0319
针对靶点:ILT7
抗体药商品名:Daxdilimab
抗体药描述:Daxdilimab (HZN-7734) is an anti-ILT7 human monoclonal antibody that depletes certain dendritic cells. Depleting these cells may interrupt the cycle of inflammation that causes tissue damage in a variety of autoimmune conditions.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ILT7
Synonyms: CD85g; ILT7
Target Description: Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G 1, 2. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Ensembl: ENSG00000239961
Uniprot: P59901