【产品概况】
产品名称:Human C2 Antibody (ARGX-117, Research Use)
产品编号:NBR-0323
针对靶点:C2
抗体药商品名:ARGX-117
抗体药描述:ARGX-117 is designed to be a humanized sweeping antibody that binds specifically to C2 in a pH- and Ca2+- dependent manner. C2 is a protein in the complement cascade which, when activated, leads to cell destruction. Binding of ARGX-117 is intended to inhibit the function of C2 and downstream complement activation.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: C2
Synonyms:
Target Description: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
Ensembl: ENSG00000166278
Uniprot: P06681