【产品概况】
产品名称:Human C3 Antibody (NGM621, Research Use)
产品编号:NBR-0324
针对靶点:C3
抗体药商品名:NGM621
抗体药描述:NGM621 is a humanized IgG1 monoclonal antibody engineered to potently inhibit complement C3. We believe that there are multiple possible areas of differentiation for NGM621 based on efficacy, dosing frequency and safety.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: C3
Synonyms: ARMD9; C3a; C3b; CPAMD1
Target Description: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
Ensembl: ENSG00000125730
Uniprot: P01024