【产品概况】
产品名称:Human CD45 Antibody (Apamistamab, Research Use)
产品编号:NBR-0348
针对靶点:CD45
抗体药商品名:Apamistamab
抗体药描述:Apamistamab (Iomab-B) is a targeted therapy being developed for AML, comprised of a monoclonal antibody that is connected to radioactive material (making it a radiolabeled antibody).apamistamab (Iomab-B) is currently being studied in the SIERRA clinical trial.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD45
Synonyms: CD45; GP180; LCA; T200
Target Description: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Ensembl: ENSG00000081237
Uniprot: P08575