【产品概况】
产品名称:Human Integrin A4 & B7 Antibody ( Vedolizumab, Research Use)
产品编号:NBR-0350
针对靶点:Integrin A4 & B7
抗体药商品名: Vedolizumab
抗体药描述:Vedolizumab is a humanized monoclonal antibody that was developed to reduce lymphocyte trafficking to the intestine by specifically targeting the α4β7 heterodimer, which is expressed on the surface of gut-specific lymphocytes.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Integrin A4 & B7
Synonyms: CD49D
Target Description: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1.
Ensembl: ENSG00000115232
Uniprot: P13612