【产品概况】
产品名称:Human IL-1B Antibody (Canakinumab, Research Use)
产品编号:NBR-0396
针对靶点:IL-1B
抗体药商品名:Canakinumab
抗体药描述:Canakinumab (ACZ885, Ilaris) is a human anti-IL-1β monoclonal antibody developed by Novartis. its mode of action is based on the neutralization of 1β signaling, resulting in suppression of inflammation in patients with disorders of autoimmune origin.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-1B
Synonyms: IL-1B; IL1-BETA; IL1F2
Target Description: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Ensembl: ENSG00000125538
Uniprot: P01584