【产品概况】
产品名称:Human EFNA4 Antibody (PF-06647263, Research Use)
产品编号:NBR-0433
针对靶点:EFNA4
抗体药商品名:PF-06647263
抗体药描述:PF-06647263, a novel antibody-drug conjugate consisting of an anti-EFNA4 antibody linked to a calicheamicin payload, has shown potent antitumor activity in human xenograft tumor models, including triple-negative breast cancer (TNBC).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: EFNA4
Synonyms: EPLG4; LERK4
Target Description: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.
Ensembl: ENSG00000243364
Uniprot: P52798