【产品概况】
产品名称:Human FCgR3A Antibody ( AFM13, Research Use)
产品编号:NBR-0445
针对靶点:FCgR3A
抗体药商品名: AFM13
抗体药描述:The CD30/CD16A-bispecific antibody AFM13 is an innate immune cell engager, a first-in-class, tetravalent antibody, designed to create a bridge between CD30 on HL cells and the CD16A receptor on natural killer cells and macrophages, to induce tumor cell killing.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FCgR3A
Synonyms: CD16; CD16a; FCG3; FCGR3
Target Description: Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).
Ensembl: ENSG00000203747
Uniprot: P08637