【产品概况】
产品名称:Human C5 Antibody (Eculizumab, Research Use)
产品编号:NBR-0454
针对靶点:C5
抗体药商品名:Eculizumab
抗体药描述:Eculizumab is a recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: C5
Synonyms: C5a; C5b; CPAMD4
Target Description: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Ensembl: ENSG00000106804
Uniprot: P01031