【产品概况】
产品名称:Human Amyloid Beta Antibody (GSK 933776, Research Use)
产品编号:NBR-0504
针对靶点:Amyloid Beta
抗体药商品名:GSK 933776
抗体药描述:GSK933776 is a humanized mouse IgG1 monoclonal antibody directed against the N-terminus of the Aβ peptide. Its Fc region has been engineered to reduce FC-receptor binding and complement activation; this was done in an effort to weaken the antibody's effector function and minimize risk of side effects such as ARIA.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: APP
Synonyms: AD1
Target Description: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis 1.
Ensembl: ENSG00000142192
Uniprot: P05067