【产品概况】
产品名称:Human Complement C5aR1 Antibody (Avdoralimab, Research Use)
产品编号:NBR-0513
针对靶点:Complement C5aR1
抗体药商品名:Avdoralimab
抗体药描述:Avdoralimab (IPH 5401) is a fully human IgGκ monoclonal antibody that targets the complement C5a receptor 1 (C5aR1) that prevents its binding to C5a. Avdoralimab can be used for complement-driven inflammatory diseases and solid tumours research.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: C5AR1
Synonyms: C5A; C5AR; C5R1; CD88
Target Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events.
Ensembl: ENSG00000197405
Uniprot: P21730