【产品概况】
产品名称:Human BACE1 Antibody (Genentech anti-BACE1, Research Use)
产品编号:NBR-0529
针对靶点:BACE1
抗体药商品名:Genentech anti-BACE1
抗体药描述:The drug is a recombinant fully human anti-BACE1 monoclonal antibody, being developed by Genentech.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: BACE1
Synonyms: N/A
Target Description: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Ensembl: ENSG00000186318
Uniprot: P56817