Human PCSK9 Antibody (Bococizumab, Research Use)

产品名称	Human PCSK9 Antibody (Bococizumab, Research Use)
目录号	NBR-0531
别名	FH3; HCHOLA3; NARC-1
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0531-100UG	100ug	￥550	请咨询
NBR-0531-1MG	1mg	￥3500	请咨询
NBR-0531-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human PCSK9 Antibody (Bococizumab, Research Use)
产品编号：NBR-0531
针对靶点：PCSK9
抗体药商品名：Bococizumab
抗体药描述：Bococizumab (formerly RN316/PF-04950615) is a humanized IgG2 (delta) monoclonal antibody being developed by Pfizer . From phase 1 and 2a trials it has been reported to provide up to approximately 75% reduction in LDL-C levels

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: PCSK9
Synonyms: FH3; HCHOLA3; NARC-1
Target Description: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments.
Ensembl: ENSG00000169174
Uniprot: Q8NBP7