【产品概况】
产品名称:Human CB1 / CNR1 Antibody (Nimacimab, Research Use)
产品编号:NBR-0537
针对靶点:CB1 / CNR1
抗体药商品名:Nimacimab
抗体药描述:Nimacimab is the first and only known clinical stage negative-allosteric modulating antibody to the CB1 receptor in clinical trials. Nimacimab is a multi-modal therapeutic candidate with anti-fibrotic, anti-inflammatory, and beneficial metabolic mechanisms of action.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CNR1
Synonyms: CANN6; CB-R; CB1; CB1A; CB1K5; CNR
Target Description: G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrahydrocannabinol (THC).
Ensembl: ENSG00000118432
Uniprot: P21554