【产品概况】
产品名称:Human TIM-3 / HAVCR2 / CD366 Antibody (Cobolimab, Research Use)
产品编号:NBR-0551
针对靶点:TIM-3 / HAVCR2 / CD366
抗体药商品名:Cobolimab
抗体药描述:Cobolimab is a monoclonal antibody against the inhibitory T-cell receptor, T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), with potential immune checkpoint inhibitory and antineoplastic activities.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: HAVCR2
Synonyms: CD366; FLJ14428; Tim-3; TIM3; TIMD3
Target Description: Cell surface receptor implicated in modulating innate and adaptive immune responses. Generally accepted to have an inhibiting function. Reports on stimulating functions suggest that the activity may be influenced by the cellular context and/or the respective ligand.
Ensembl: ENSG00000135077
Uniprot: Q8TDQ0