【产品概况】
产品名称:Human CD19 Antibody (Coltuximab, Research Use)
产品编号:NBR-0553
针对靶点:CD19
抗体药商品名:Coltuximab
抗体药描述:Coltuximab ravtansine (CoR) or SAR3419 is an anti-CD19 monoclonal antibody linked to the tubulin inhibitor maytansinoid DM4, which demonstrated efficacy in vitro and in vivo in ALL, as well as safety in a lymphoma phase I study.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD19
Synonyms: N/A
Target Description: Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.
Ensembl: ENSG00000177455
Uniprot: P15391