【产品概况】
产品名称:Human CD47 Antibody (Ligufalimab, Research Use)
产品编号:NBR-0581
针对靶点:CD47
抗体药商品名:Ligufalimab
抗体药描述:Ligufalimab, also known as AK117, is a humanized IgG4 monoclonal antibody with a unique structure. Ligufalimab could effectively eliminate RBC hemagglutination and anemia, and induce robust macrophage-mediated phagocytosis of cancer cells, and improve the antitumor efficacy without the requirement of a lower 'priming' dose to prevent anemia.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD47
Synonyms: IAP; MER6; OA3
Target Description: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus.
Ensembl: ENSG00000196776
Uniprot: Q08722