Human TIGIT Antibody (Domvanalimab, Research Use)

产品名称	Human TIGIT Antibody (Domvanalimab, Research Use)
目录号	NBR-0588
别名	VSIG9; VSTM3
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0588-100UG	100ug	￥550	请咨询
NBR-0588-1MG	1mg	￥3500	请咨询
NBR-0588-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human TIGIT Antibody (Domvanalimab, Research Use)
产品编号：NBR-0588
针对靶点：TIGIT
抗体药商品名：Domvanalimab
抗体药描述：Domvanalimab, an anti-TIGIT antibody, showed clinically meaningful results as an Fc-silent anti-TIGIT/anti-PD-1 combination therapy for patients with first-line metastatic non-small cell lung cancer (NSCLC) at a fourth interim analysis.

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: TIGIT
Synonyms: VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Ensembl: ENSG00000181847
Uniprot: Q495A1