【产品概况】
产品名称:Human PDCD1 / PD-1 / CD279 Antibody (Dostarlimab, Research Use)
产品编号:NBR-0591
针对靶点:PDCD1 / PD-1 / CD279
抗体药商品名:Dostarlimab
抗体药描述:Dostarlimab is a new drug previously used to treat endometrial cancers and has a mechanism of action that is in accordance with other PD-1/PD-L1 inhibitors. A recent clinical trial has found Dostarlimab to cure 100% of the CRC patients who were given this drug while also showing no adverse events of grade 3 or higher in any patient.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD279
Synonyms: PD1; CD279; HSLE1
Target Description: PDCD1 (Programmed Cell Death 1) is a Protein Coding gene. Diseases associated with PDCD1 include Systemic Lupus Erythematosus 2 and Multiple Sclerosis. Among its related pathways are Disease and SARS-CoV-2 Infection. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity.
Ensembl: ENSG00000188389
Uniprot: Q15116