【产品概况】
产品名称:Human CEACAM5 / CEA / CD66e Antibody (CergutuzumAb, Research Use)
产品编号:NBR-0598
针对靶点:CEACAM5 / CEA / CD66e
抗体药商品名:CergutuzumAb
抗体药描述:Cergutuzumab amunaleukin is a novel monomeric CEA-targeted immunocytokine, that comprises a single IL-2 variant (IL2v) moiety with abolished CD25 binding, fused to the C-terminus of a high affinity, bivalent carcinoembryonic antigen (CEA)-specific antibody devoid of Fc-mediated effector functions.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD66e
Synonyms: CD66e; CEA
Target Description: CEACAM5 (CEA Cell Adhesion Molecule 5) is a Protein Coding gene. Diseases associated with CEACAM5 include Bile Duct Cancer and Lung Cancer. Among its related pathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and GPI anchor binding. An important paralog of this gene is CEACAM1.
Ensembl: ENSG00000105388
Uniprot: P06731