【产品概况】
产品名称:Human IL-12b Antibody (Ebdarokimab, Research Use)
产品编号:NBR-0599
针对靶点:IL-12b
抗体药商品名:Ebdarokimab
抗体药描述:Ebdarokimab is a fully human monoclonal antibody (mAb) targeting IL-12/IL-23 pathway. It specifically binds to the P40 subunit of both IL-12 and IL-23, resulting in inhibition of the signaling of IL-12 and IL-23 cytokines.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-12b
Synonyms: CLMF2; NKSF2; CLMF
Target Description: IL12B (Interleukin 12B) is a Protein Coding gene. Diseases associated with IL12B include Immunodeficiency 29 and Takayasu Arteritis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity.
Ensembl: ENSG00000113302
Uniprot: P29460