【产品概况】
产品名称:Human CEACAM5 / CEA / CD66e Antibody (Tusamitamab, Research Use)
产品编号:NBR-0600
针对靶点:CEACAM5 / CEA / CD66e
抗体药商品名:Tusamitamab
抗体药描述:Tusamitamab ravtansine is a potential first-in-class antibody-drug conjugate (ADC) targeting CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5), a cell-surface glycoprotein that is highly expressed in non-small cell lung cancer (NSCLC), gastric cancer and other cancers.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD66e
Synonyms: CD66e; CEA
Target Description: CEACAM5 (CEA Cell Adhesion Molecule 5) is a Protein Coding gene. Diseases associated with CEACAM5 include Bile Duct Cancer and Lung Cancer. Among its related pathways are Metabolism of proteins and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and GPI anchor binding. An important paralog of this gene is CEACAM1.
Ensembl: ENSG00000105388
Uniprot: P06731