【产品概况】
产品名称:Human PCSK9 Antibody (Ebronucimab, Research Use)
产品编号:NBR-0601
针对靶点:PCSK9
抗体药商品名:Ebronucimab
抗体药描述:Ebronucimab (AK102) is a novel fully human immunoglobulin G1 (IgG1) monoclonal antibody against PCSK9.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PCSK9
Synonyms: NARC-1; FH3; HCHOLA3
Target Description: PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) is a Protein Coding gene. Diseases associated with PCSK9 include Hypercholesterolemia, Familial, 3 and Homozygous Familial Hypercholesterolemia. Among its related pathways are Plasma lipoprotein assembly, remodeling, and clearance and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). Gene Ontology (GO) annotations related to this gene include RNA binding and protein self-association. An important paralog of this gene is TPP2
Ensembl: ENSG00000169174
Uniprot: Q8NBP7