【产品概况】
产品名称:Human Complement C5 Antibody (Ravulizumab, Research Use)
产品编号:NBR-0608
针对靶点:Complement C5
抗体药商品名:Ravulizumab
抗体药描述:Ravulizumab, a humanized monoclonal antibody, is a complement C5 inhibitor developed by Alexion Pharmaceuticals for the treatment of paroxysmal nocturnal haemoglobinuria (PNH) and atypical haemolytic uraemic syndrome (aHUS).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Complement C5
Synonyms: CPAMD4 ; C5; C5a
Target Description: C5 (Complement C5) is a Protein Coding gene. Diseases associated with C5 include Complement Component 5 Deficiency and Eculizumab, Poor Response To. Among its related pathways are Complement cascade and Immune response Lectin induced complement pathway. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and endopeptidase inhibitor activity. An important paralog of this gene is C3.
Ensembl: ENSG00000106804
Uniprot: P01031