【产品概况】
产品名称:Human Complement Factor D Antibody (Lampalizumab, Research Use)
产品编号:NBR-0611
针对靶点:Complement Factor
抗体药商品名:DLampalizumab
抗体药描述:Lampalizumab (INN) is an antigen-binding fragment of a humanized monoclonal antibody that binds to complement factor D; it was developed as a potential treatment of geographic atrophy (atrophy of the retinal cells, retinal pigment epithelium, and choriocapillaris) secondary to age-related macular degeneration.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: Complement Factor D
Synonyms: ADN; PFD; DF
Target Description: CFD (Complement Factor D) is a Protein Coding gene. Diseases associated with CFD include Complement Factor D Deficiency and Meningococcemia. Among its related pathways are Initial triggering of complement and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is F12.
Ensembl: ENSG00000197766
Uniprot: P00746