【产品概况】
产品名称:Human CSF1R / M-CSFR / CD115 Antibody (Emactuzumab, Research Use)
产品编号:NBR-0613
针对靶点:CSF1R / M-CSFR / CD115
抗体药商品名:Emactuzumab
抗体药描述:Emactuzumab, also known as RG-7155, is a humanized monoclonal antibody developed by Genentech/Roche. It was designed to directly against the tyrosine kinase receptor colony stimulating factor 1 receptor (CSF1R), which is also known as macrophage colony-stimulating factor receptor (M-CSFR) and Cluster of Differentiation 115 (CD115).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CSF1R
Synonyms: C-FMS; CSFR; CD115
Target Description: CSF1R (Colony Stimulating Factor 1 Receptor) is a Protein Coding gene. Diseases associated with CSF1R include Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1 and Brain Abnormalities, Neurodegeneration, And Dysosteosclerosis. Among its related pathways are GPCR Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is KIT.
Ensembl: ENSG00000182578
Uniprot: P07333