【产品概况】
产品名称:Human CSF2 / GM-CSF Antibody (Namilumab, Research Use)
产品编号:NBR-0617
针对靶点:CSF2 / GM-CSF
抗体药商品名:Namilumab
抗体药描述:Namilumab (AMG203), an immunoglobulin G1 monoclonal antibody that binds with high affinity to granulocyte-macrophage colony-stimulating factor (GM-CSF), was evaluated in a phase II randomized, double-blind, placebo-controlled study to investigate the efficacy and safety in patients with rheumatoid arthritis (RA) with an inadequate response to methotrexate (MTX-IR) or anti-tumour necrosis factor therapy (TNF-IR).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CSF2
Synonyms: GMCSF; Sargramostim; GM-CSF
Target Description: CSF2 (Colony Stimulating Factor 2) is a Protein Coding gene. Diseases associated with CSF2 include Pulmonary Alveolar Proteinosis and Mucositis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and Gene expression (Transcription). Gene Ontology (GO) annotations related to this gene include cytokine activity and granulocyte macrophage colony-stimulating factor receptor binding.
Ensembl: ENSG00000164400
Uniprot: P04141